Table 2.
Multiple centralities of targets in G-C-T-V network (MCC ≥ 30).
| Node | Annotation | Local-based method | Global-based method | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCC | DMNC | MNC | Degree | EPC | Bottle Neck | Ec Centricity | Closeness | Radiality | Betweenness | Stress | ||
| PTGS2 | Prostaglandin-Endoperoxide Synthase 2 | 62 | 0 | 1 | 66 | 27.172 | 1 | 0.25 | 170.4167 | 3.82428 | 4497.1270 | 148412 |
| NCOA1 | Nuclear Receptor Coactivator 1 | 36 | 0 | 1 | 39 | 21.072 | 1 | 0.25 | 153.0833 | 3.65815 | 1082.7710 | 52242 |
| SCN5A | Sodium Voltage-Gated Channel A Subunit 5 | 36 | 0 | 1 | 38 | 22.735 | 1 | 0.25 | 153.0833 | 3.65815 | 879.1755 | 49214 |
| ADRB2 | Adrenoceptor B 2 | 35 | 0 | 1 | 38 | 22.861 | 1 | 0.25 | 152.4167 | 3.65176 | 724.7611 | 48948 |
| NCOA2 | Nuclear Receptor Coactivator 2 | 33 | 0 | 1 | 38 | 18.692 | 1 | 0.25 | 151.0833 | 3.63898 | 2341.6570 | 62710 |
| PTGS1 | Prostaglandin-Endoperoxide Synthase 1 | 33 | 0 | 1 | 36 | 21.744 | 1 | 0.25 | 151.0833 | 3.63898 | 1046.6570 | 59386 |
| CHRM1 | Cholinergic Receptor Muscarinic 1 | 32 | 0 | 1 | 35 | 21.879 | 1 | 0.25 | 150.4167 | 3.63259 | 633.7786 | 43362 |
| CHRNA7 | Cholinergic Receptor Nicotinic A 7 Subunit | 31 | 0 | 1 | 34 | 21.611 | 1 | 0.25 | 149.7500 | 3.62620 | 534.4842 | 40906 |
| F2 | Coagulation Factor II, Thrombin | 31 | 0 | 1 | 32 | 16.676 | 1 | 0.25 | 149.7500 | 3.62620 | 853.0783 | 29594 |
| RXRA | Retinoid X Receptor A | 30 | 0 | 1 | 33 | 19.255 | 1 | 0.25 | 149.0833 | 3.61981 | 647.0734 | 40368 |
| ACHE | Acetylcholinesterase | 30 | 0 | 1 | 31 | 16.274 | 1 | 0.25 | 149.0833 | 3.61981 | 873.2213 | 28376 |
| CA2 | Carbonic Anhydrase 2 | 30 | 0 | 1 | 31 | 17.575 | 15 | 0.25 | 155.0833 | 3.77316 | 2965.7050 | 65226 |
MCC, maximal clique centrality; DMNC, density of maximum neighborhood component; MNC, maximum neighborhood component; EPC, edge percolated component.