TABLE 2.

Functional gene group changes.

Pathway description (number of genes)	ME7 + saline	ME7 + SL3261
Long-term potentiation (n = 31)	0.7992	0.6790
Long-term depression (n = 22)	0.7845	0.6899
Postsynaptic density (n = 16)	0.7913	0.7188
Neuronal receptors (n = 20)	0.7823	0.6623
Other structural/plasticity genes (n = 32)	0.9506	0.8011

Fold change in expression compared to NBH mice 4 weeks after systemic bacterial challenge with S. typhimurium SL3261 at 8-wpi in ME7 prion mice.