Table 3.
Correlation between CAF-derived exosomal content and clinical pathological characterizations of cancer patients.
| Exosomal contents | Tumor type | Sample sources | Dyregulation | Relationship with clinicopathology | Ref. |
|---|---|---|---|---|---|
| miR-382-5p | Oral squamous cell carcinoma | Tissue | Upregulation | TNM stage, lymph node metastasis | (135) |
| miR196a | Head and neck cancer | Plasma | Upregulation | Poor prognosis | (146) |
| miR-3188 | Head and neck cancer | Plasma and tissue | Downregulation | TNM stage, tumor size, poor survival | (126) |
| miR-150-3p | Hepatocellular carcinoma | Plasma | Downregulation | Long survival | (61) |
| miR369 | Lung squamous cell carcinoma | Tissue | Upregulation | Poor prognosis | (138) |
| miR-17-5p | Colorectal cancer | Tissue | Upregulation | Poor prognosis | (113) |
| lncRNA H19 | Colorectal cancer | Tissue | Upregulation | TNM stage | (115) |
| lncRNA UCA1 | Vulvar squamous cell carcinoma | Tissue | Upregulation | T stage, Clinical stage, and lymph node metastasis status | (145) |
| MMP11 | Gastric cancer | Tissue | Upregulation | Poor prognosis | (47) |