TABLE 2.
Markers of inflammation at baseline and after RYGB in patients with diabetes and normal glucose tolerance before and 1‐week, 3 months, and 1‐year after RYGB
| Diabetes | NGT | Mixed effect model ANOVA | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Before | 1‐week | 3 months | 1‐year | Before | 1‐week | 3 months | 1‐year | Time | Group | Time x Group | |
| Ferritin (µg/L) | 144 ± 27 | 219 ± 55 | 81 ± 19 | 50 ± 14 | 77 ± 24 | 121 ± 28 | 41 ± 12 | 30 ± 8 | <0.01 | 0.04 | 0.07 |
| hs‐CRP (mg/L) | 7.8 ± 2.6 | 21.9 ± 4.9 | 4.8 ± 1.3 | 1.3 ± 0.7 | 4.4 ± 0.9 | 27.2 ± 9.1 | 3.2 ± 0.7 | 1.3 ± 0.5 | <0.01 | 0.39 | 0.51 |
| IL‐6 (ng/L) | 5.4 ± 0.8 | 5.9 ± 0.5 | 4.8 ± 0.4 | 3.8 ± 1.6 | 5.3 ± 0.6 | 8.5 ± 1.5 | 4.8 ± 0.3 | 7.3 ± 3.5 | 0.16 | 0.93 | 0.34 |
| MCP‐1 (pg/ml) | 280 ± 26 | 302 ± 31 | 260 ± 32 | 254 ± 29 | 315 ± 43 | 264 ± 18 | 319 ± 57 | 248 ± 23 | 0.01 | 0.46 | 0.20 |
| TNF‐α (pg/ml) | 1.7 ± 0.2 | 2.0 ± 0.3 | 1.8 ± 0.1 | 1.4 ± 0.2 | 1.8 ± 0.2 | 1.9 ± 0.2 | 1.9 ± 0.1 | 1.7 ± 0.1 | 0.16 | 0.53 | 0.58 |
Parameters are presented as means ± standard error of mean.
Abbreviations: Hs‐CRP, high sensitivity C‐reactive protein; IL‐6, interleukin 6; MCP‐1, monocyte chemoattractant protein‐1; NGT, normal glucose tolerance; TNF‐α, tumor necrosis factor‐α.