. 2021 Nov 8;43(3):1032–1046. doi: 10.1002/hbm.25705

TABLE 4.

Statistical results for the nodal graph theoretical metrics that differed (FDR corrected p <.05) between the uninjured, typically developing (TD) children and the mild traumatic brain injury (mTBI) and orthopedic injury (OI) groups

											95% confidence interval
Nodal metric	Node	Model predictor	F‐value	p‐value ^a	Contrast	β	SE	t‐value	Permutation p‐value	Cohen's d	Lower	Upper
Degree centrality (Dc)	Fusiform gyrus	Group	*12.71*	*<.001*	TD–OI	*6.04*	*1.35*	*4.49*	*<.001*	*0.96*	*0.54*	*1.38*
					TD–mTBI	*5.07*	*1.14*	*4.45*	*<.001*	*0.80*	*0.45*	*1.16*
					OI–mTBI	−9.69e−01	1.16	−0.83	.999	−0.15	−0.52	0.21
		Hemisphere	*148.99*	*<.001*	**Left–right**	*8.65*
		Age	0.01	0.933		0.017
		Sex	5.81	0.017	Female–male	2.31
Clustering coefficient (NCp)	Superior orbital gyrus	Group	*5.67*	*<.001*	*TD–OI*	*0.019*	*7.06e−03*	*2.75*	*.019*	*0.68*	*0.19*	*1.17*
					*TD–mTBI*	*0.019*	*5.98e−03*	*3.17*	*<.001*	*0.66*	*0.25*	*1.08*
					OI–mTBI	−5.18e−04	6.11e−03	−0.08	.999	−0.02	−0.44	0.41
		Hemisphere	*39.47*	*<.001*	*Left–right*	*−2.01e−02*
		Age	1.58	.211		1.36e−03
		Sex	<0 .01	.927	Female–male	4.63e−04
	Middle orbital gyrus	Group	*7.76*	*0.001*	TD–OI	*3.27e−02*	*8.79e−03*	*3.72*	*<.001*	*0.95*	*0.44*	*1.45*
					TD–mTBI	*2.38e−02*	*7.44e−03*	*3.20*	*<.001*	*0.69*	*0.26*	*1.11*
					OI–mTBI	−8.85e−03	7.60e−03	−1.16	1.000	−0.26	−0.69	0.18
		Hemisphere	*53.47*	*<.001*	**Left–right**	*−2.83e−02*
		Age	1.08	0.301		1.40e−03
		Sex	0.33	0.566	Female–male	−3.59e−03
	Insula	Group	6.85	0.001	TD–OI	*1.96e−02*	*6.42e−03*	*3.04*	*<.001*	*0.78*	*0.27*	*1.29*
					TD–mTBI	*1.89e−02*	*5.44e−03*	*3.47*	*<.001*	*0.75*	*0.32*	*1.18*
					OI–mTBI	−6.85e−04	5.55e−03	−0.12	.999	−0.03	−0.47	0.41
		Hemisphere	0.04	0.834	Left–right	−5.90e−04
		Age	5.70	0.018		2.35e−03
		Sex	5.30	0.023	Female–male	1.05e−02
	Thalamus	Group	*7.43*	*0.001*	TD–OI	*2.40e−02*	*8.31e−03*	*2.89*	*<.001*	*1.65*	*0.52*	*2.78*
					TD–TBI	*2.63e−02*	*7.04e−03*	*3.74*	*<.001*	*1.81*	*0.85*	*2.76*
					OI–TBI	2.34e−03	7.18e−03	0.33	0.668	0.16	−0.81	1.14
		Hemisphere	1.45	0.231	Left–right	−1.96e−03
		Age	6.30	0.013		3.20e−03
		Sex	0.18	0.670	Female–male	2.52e−03
	Paracentral lobule	Group	*5.80*	*<.001*	TD–OI	*1.51e−02*	*.03‐e03*	*2.49*	*.011*	*0.45*	*0.09*	*0.81*
					TD–mTBI	*1.64e−021*	*.11‐e03*	*3.21*	*.001*	*0.49*	*0.19*	*0.79*
					OI–mTBI	*1.36e−03*	5.22‐e03	0.26	.796	0.04	−0.27	0.35
		Hemisphere	*17.55*	*<.001*	**Left–right**	*1.57e−02*
		Age	*6.38*	*.013*		*2.34e−03*
		Sex	0.07	.788	Female–male	1.16e−03
Efficiency (Ne)	Fusiform gyrus	Group	*12.71*	*<.001*	TD–OI	*3.39e−02*	*7.56e−03*	*4.49*	*<.001*	*0.95*	*0.53*	*1.38*
					TD–TBI	*2.85e−02*	*6.40e−03*	*4.45*	*<.001*	*0.80*	*0.45*	*1.16*
					OI–TBI	−5.43e−03	6.54e−03	−0.83	1.000	−0.15	−0.52	0.21
		Hemisphere	*148.84*	*<.001*	**Left–right**	*4.86e−02*
		Age	0.01	0.935		9.43e−05
		Sex	5.80	0.017	Female–male	1.29e−02
Shortest path length (NLp)	Fusiform gyrus	Group	*11.91*	*<.001*	TD–OI	*−4.58e−02*	*1.05e−02*	*−4.35*	*<.001*	*−0.90*	*−1.31*	*−0.49*
					TD–TBI	*−3.84e−02*	*8.92e−03*	*−4.31*	*<.001*	*−0.75*	*−1.10*	*−0.41*
					OI–TBI	7.41e−03	9.11e−03	0.81	0.437	0.15	−0.21	0.50
		Hemisphere	*135.35*	*<.001*	**Left–right**	*−6.65e−02*
		Age	0.00	0.990		2.04e−05
		Sex	5.66	0.019	Female–male	−1.78e−02

Unadjusted p‐value reported. Italicized and bolded = corrected p‐value <.05; Underlined = |Cohen's d| ≥.80 (i.e., ≥ large effect size).