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. 2021 Nov 5;43(3):1011–1031. doi: 10.1002/hbm.25703

FIGURE 4.

FIGURE 4

Brain activations and deactivations related to the threat of auditory stressors. (a) Statistical parametric maps illustrating the main effect of threat. The colored bar indicates the t‐value (+20 to −20) of the activation height. Cortical areas evidencing increased (orange‐red color) and decreased (green‐blue color) activations during the threat versus safe conditions are shown. For illustrative purposes, maps are thresholded at p < .005 FDR corrected. Activations are superimposed on a subject anatomical T1 scan, normalized to the standard MNI space. ACC, anterior cingulate cortex; DMPFC, dorsomedial prefrontal cortex; PC, parietal cortex (inferior parietal lobule); SMA, supplementary motor area; STG, superior temporal gyrus; VMPFC, ventromedial prefrontal cortex (orbitofrontal cortex). (b) Barplots show the percentage of BOLD signal increase/decrease at peak voxel for threat and safe conditions relative to rest condition. MNI coordinates are indicated. The percentage is calculated over all blocks, that is, 0‐back and 2‐back, for each threat level. Error bars are SEM. Plain bar = safe, striped bar = threat