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. 2022 Jan 18;22:126. doi: 10.1186/s12889-021-12479-w

Table 3.

Results of the fully adjusted multinomial logistic regression analyses at wave 1

Predictors Undecided Unwilling
RRR 95% CI P-value RRR 95% CI P-value
Sex
 Male reference reference
 Female 1.19 (1.07–1.32) 0.001 1.13 (0.96–1.32) 0.145
Age group, years
 65+ reference reference
 50–64 2.35 (2.04–2.70) < 0.001 1.82 (1.44–2.29) < 0.001
 30–49 3.58 (3.06–4.19) < 0.001 3.04 (2.35–3.91) < 0.001
 18–29 4.16 (3.35–5.16) < 0.001 4.46 (3.23–6.15) < 0.001
Highest education
 Junior/senior high school 1.21 (1.09–1.35) < 0.001 1.32 (1.11–1.56) 0.001
 Two- or three-year college 1.08 (0.96–1.22) 0.185 1.28 (1.06–1.54) 0.009
 Four-year college or higher reference reference
Family members living together
 Living alone 1.33 (1.15–1.54) < 0.001 1.46 (1.16–1.84) 0.001
 Living only with spouses reference reference
 Living with children 1.15 (1.02–1.29) 0.027 1.20 (0.98–1.47) 0.082
 Living with parents 1.34 (1.16–1.55) < 0.001 1.46 (1.16–1.84) 0.001
 Three generation household 1.49 (1.21–1.83) < 0.001 1.40 (0.99–1.98) 0.059
 Others (siblings only, friends, grandparents and grandchildren etc.) 1.38 (0.97–1.96) 0.077 1.88 (1.17–3.00) 0.009
Employment
 Employed reference reference
 Homemaker 1.09 (0.95–1.25) 0.208 0.86 (0.68–1.08) 0.198
 Not employed (seeking a job) 0.98 (0.74–1.28) 0.858 0.98 (0.67–1.45) 0.937
 Not employed (not seeking job) 1.06 (0.91–1.24) 0.437 1.29 (1.03–1.61) 0.026
 Student 0.88 (0.64–1.21) 0.420 0.72 (0.46–1.11) 0.137
 Other 1.60 (1.05–2.42) 0.028 1.99 (1.14–3.47) 0.015
Annual household income, million yen
 < 3 1.35 (1.15–1.58) < 0.001 1.39 (1.09–1.77) 0.008
 3–4 0.99 (0.86–1.14) 0.871 0.96 (0.77–1.20) 0.730
 5–7 1.12 (0.98–1.28) 0.086 0.87 (0.70–1.08) 0.216
 ≥ 8 reference reference
Bank and saving deposit amount, million yen
 < 1 1.44 (1.27–1.64) < 0.001 1.45 (1.18–1.77) < 0.001
 1–3 1.23 (1.08–1.40) 0.002 1.13 (0.92–1.40) 0.242
 4–9 1.23 (1.08–1.39) 0.001 1.13 (0.92–1.39) 0.238
 ≥ 10 reference reference
BMI
 < 18.5 1.17 (1.03–1.34) 0.019 1.34 (1.10–1.62) 0.003
 18.5–24.9 reference reference
 25.0-29.9 0.94 (0.83–1.07) 0.341 1.02 (0.84–1.25) 0.827
 ≥ 30.0 0.97 (0.75–1.26) 0.833 0.76 (0.49–1.19) 0.232
Pre-existing condition
 Hypertension 0.79 (0.69–0.90) < 0.001 0.62 (0.49–0.78) < 0.001
 Dyslipidemia 0.62 (0.52–0.73) < 0.001 0.68 (0.51–0.91) 0.009
 Diabetes 0.95 (0.77–1.17) 0.610 0.88 (0.62–1.27) 0.501
 Heart disease 0.86 (0.63–1.17) 0.338 0.94 (0.56–1.56) 0.802
 Renal disease 1.12 (0.67–1.85) 0.674 0.70 (0.27–1.81) 0.467
 Cancer 0.74 (0.50–1.09) 0.126 0.82 (0.44–1.52) 0.522
 Respiratory disease 0.97 (0.71–1.31) 0.838 1.23 (0.78–1.92) 0.369
 Other condition 1.03 (0.71–1.47) 0.890 1.02 (0.58–1.77) 0.952
Region of residence
 Tokyo reference reference
 Kanagawa 1.05 (0.85–1.29) 0.652 0.64 (0.45–0.90) 0.011
 Osaka 0.93 (0.75–1.14) 0.479 0.83 (0.60–1.13) 0.237
 Aichi 0.90 (0.72–1.12) 0.343 0.80 (0.57–1.11) 0.180
 Saitama 1.12 (0.90–1.39) 0.319 0.69 (0.48–1.00) 0.049
 Chiba 0.93 (0.73–1.17) 0.525 1.05 (0.75–1.47) 0.776
 Hyogo 0.92 (0.72–1.17) 0.496 0.87 (0.61–1.25) 0.457
 Hokkaido 0.86 (0.67–1.10) 0.225 0.80 (0.55–1.15) 0.227
 Fukuoka 0.84 (0.64–1.09) 0.187 1.01 (0.70–1.46) 0.964
 Tohoku region 0.74 (0.59–0.91) 0.005 0.61 (0.44–0.86) 0.004
 North Kanto 1.15 (0.92–1.45) 0.228 0.84 (0.59–1.22) 0.365
 Hokuriku 0.92 (0.71–1.18) 0.501 0.64 (0.42–0.97) 0.037
 Chubu 1.06 (0.86–1.30) 0.593 0.67 (0.47–0.93) 0.019
 Kinki 0.96 (0.78–1.19) 0.713 0.96 (0.71–1.31) 0.817
 Chugoku 1.30 (1.05–1.63) 0.018 0.89 (0.63–1.27) 0.535
 Shikoku 0.81 (0.60–1.09) 0.156 0.81 (0.52–1.27) 0.358
 Kyushu and Okinawa 1.10 (0.89–1.36) 0.389 0.86 (0.61–1.19) 0.354
Generalized trust
 Most people can be trusted reference reference
 Need to be very careful 1.28 (1.16–1.41) < 0.001 1.59 (1.35–1.87) < 0.001
 Don’t know 1.65 (1.34–2.04) < 0.001 1.90 (1.37–2.63) < 0.001
Depression (PHQ-9)
 None (0–4) reference reference
 Mild (5–9) 1.19 (1.06–1.34) 0.003 1.30 (1.08–1.55) 0.005
 Moderate (10–14) 1.22 (1.01–1.47) 0.043 1.19 (0.89–1.59) 0.253
 Moderately severe (15–-19) 1.38 (1.04–1.82) 0.025 1.48 (0.99–2.22) 0.055
 Severe (20–27) 1.63 (1.08–2.47) 0.020 1.53 (0.87–2.71) 0.140
Generalized anxiety (GAD-7)
 Minimal (0–4) reference reference
 Mild (5–9) 1.00 (0.87–1.16) 0.965 1.03 (0.83–1.29) 0.765
 Moderate (10–14) 0.96 (0.75–1.21) 0.706 1.24 (0.88–1.75) 0.228
 Severe (15–21) 0.86 (0.60–1.23) 0.402 1.28 (0.78–2.10) 0.331
Fear of COVID-19 (FCV-19S)
 No fear (7–15) reference reference
 Mild (16–20) 0.86 (0.77–0.96) 0.006 0.50 (0.42–0.59) < 0.001
 Moderate (21–25) 0.90 (0.80–1.02) 0.094 0.47 (0.39–0.56) < 0.001
 Severe (26–35) 0.74 (0.62–0.87) < 0.001 0.41 (0.31–0.53) < 0.001

Boldface indicates statistical significance at the 5% level (both sides). Estimates are RRRs derived from multinomial logistic regression analyses adjusting for all of generalized trust, PHQ-9, GAD-7, and FCV-19S, plus other explanatory variables (sex, age group, level of education, family members living together, employment, annual household income, bank and saving deposit amount, BMI, pre-existing conditions, and region of residence). All explanatory variables are those at wave 1. Willingness to be vaccinated at wave 3 was the outcome reference group

RRR Relative Risk Ratio, CI Confidence Interval, PHQ-9 Patient Health Questionnaire-9, GAD-7 Generalized Anxiety Disorder −7, FCV-19S Fear of COVID-19 Scale