FIG 1.
Distribution of Afa/Dr fimbrial genes in strains belonging to the ST131 lineage; (A) clade A, B, and C; and (B) subclade C1 and C2. The percentage of strains containing Afa/Dr fimbriae was determined by tBLASTn against afaCEC958, with a cut-off value of > 90% nucleotide identity and > 80% gene coverage. ST131 strains were classified in clades and subclades based on clade-specific SNPs. One-hundred and 36 ST131 strains could not be classified into any clade, and thus were excluded from the analysis. Chi-squared test was used for statistical analysis (***, P < 0.0001 for pair of C2–C1).