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. 2021 Jun 28;3(4):153–162. doi: 10.1176/appi.prcp.20210017

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© 2021 The Authors. Psychiatric Research and Clinical Practice published by Wiley Periodicals LLC. on behalf of the American Psychiatric Association

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Relationship between alcohol abuse (AUD) and CRF levels. The strength for the differentiation of PTSD from control participants is evident in PTSD subjects with alcohol use (AUD). Wilcoxon p is 0.0038 in PTSD with AUD (N = 26) versus Controls (N = 64) and 0.02 in PTSD without AUD (N = 27) versus Controls. No differences in serum CRF levels are found when comparing PTSD participants with and without AUD. Wilcoxon Rank sum test for the group comparisons. Participants with AUD alone were excluded from the study group. CRF, corticotropin‐releasing factor; PTSD, posttraumatic stress disorder