Table 5.

Criteria for assessment of response on anemia

Clinical improvement in anemia (International Working group (IWG) consensus criteria for treatment response in myelofibrosis)44	Delphi expert-consensus panel definition of RBC-transfusion dependence and independence (applicable only for patients with baseline hemoglobin level of <100 g/l)
A minimum 20 g/l increase in hemoglobin level, or becoming transfusion independent for at least 8-week duration* *Transfusion dependency is defined by a history of at least 2 units of red blood cell transfusions in the past month	Becoming transfusion independent for at least 3-month duration* *Transfusion dependency is defined by a history of at least 2 units of red blood cell transfusions every month for at least 3 months (for a hemoglobin level of o85 g/l that was not associated with clinically overt bleeding