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. Author manuscript; available in PMC: 2022 Jan 18.
Published in final edited form as: Nat Microbiol. 2021 Jun 28;6(7):910–920. doi: 10.1038/s41564-021-00924-w

Extended Data Fig. 6. The evolution of CrvA/B/Y and functional study of CrvY.

Extended Data Fig. 6

(A) Extended cladogram from Figure 1B. (B) Linear form of extended cladogram in A. (C) Phylogeny of all sequenced CrvA, CrvB, and CrvY homologs. (D) Curvature of populations of wild-type A. fischeri or ΔcrvY. (E) Curvature of populations of V. cholera ΔcrvAB expressing an empty vector (+EV) or a plasmid with crvY from A. fischeri (+crvY). (A,B) Numbers are “Clade IDs” for reference to Table S2, which contains full composition of terminal nodes. (D) Terminal nodes are placed at the mean ± standard deviation of the sequences collapsed into each node. (D,E) Images represent 95th percentile of curvature in respective populations. Scale bars are 1μm; images within each figure panel are to scale. p-values determined by two-sided Wilcoxon rank sum test; n=300 from three biological replicates.