Table 1.

Baseline characteristics of the systemic sclerosis population (n = 40) and their correlations with galectin-3 and sST2 levels

Clinical variable		Value	Correlation with ln galectin-3		Correlations with ln galectin-3, corrected for age		Correlations with ln sST2		Correlations with ln sST2, corrected for age
			r	p	r	p	r	p	r	p
Age (years)		57.3 ± 13.7	0.059	0.719			−0.010	0.951
Body surface area (m2)		1.8 ± 0.2	0.206	0.202	0.206	0.208	0.063	0.700	0.063	0.704
Disease duration (years)		8.0 ± 6.2	0.406	0.009	0.406	0.010	0.038	0.817	0.042	0.799
Modified Rodnan skin score		12.6 ± 9.6	−0.291	0.069	−0.286	0.077	0.200	0.216	0.205	0.210
New York Heart Association functional class	I n (%)	14 (35%)	0.179	0.269	0.171	0.297	−0.021	0.899	−0.018	0.912
	II n (%)	16 (40%)
	III n (%)	10 (25%)
6-min walking distance (m)		397.6 ± 78.3	−0.107	0.516	−.086	0.607	−0.001	0.996	0.001	0.996
Modified Borg dyspnoea index		1.8 ± 1.8	0.229	0.161	0.221	0.183	−0.234	0.151	−0.263	0.111
Forced expiratory volume in 1 s (%)		92.1 ± 15.5	−0.320	0.044	−0.334	0.032	−0.067	0.682	−0.066	0.689
Forced vital capacity (%)		94.9 ± 16.0	−0.246	0.126	−0.272	0.094	−0.157	0.333	−0.160	0.330
Diffusing capacity of carbon monoxide (%)		62.7 ± 16.2	−0.318	0.045	−0.324	0.044	0.106	0.515	0.123	0.456
Erythrocyte sedimentation rate (mm/h)		19.6 ± 13.5	−0.070	0.666	−0.079	0.633	0.099	0.545	0.101	0.541
C-reactive protein (mg/l)		4.2 ± 6.8	0.092	0.572	0.104	0.527	−0.118	0.468	−0.122	0.460
Creatinine (μmol/l)		63.8 ± 13.2	−0.013	0.936	−0.042	0.802	0.000	0.999	0.005	0.976
NT-proBNP (pg/ml; ln in correlations)		177.5 ± 148.6	0.094	0.566	0.081	0.623	−0.129	0.426	−0.131	0.425
Galectin-3 (ng/ml; ln in correlations)		12.9 ± 4.0					−0.217	0.178	−0.217	0.184
sST2 (ng/ml; ln in correlations)		28.5 ± 11.3	−0.217	0.178	−0.217	0.184

Statistically significant p-values (p < 0.05) are formatted in bold