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. 2022 Jan 17;23:5. doi: 10.1186/s12868-021-00682-9

Table 8.

Aberrant functional connections in patients with schizophrenia spectrum disorders

Brain region t value Effect size p-unc p- FDR Brain region
SSDs > HCs
 Left posterior cingulate gyrus 6.38 0.150  < 0.001  < 0.001 Left orbital inferior frontal gyrus
5.17 0.130  < 0.001  < 0.001 Right orbital inferior frontal gyrus
4.35 0.110  < 0.001 0.005 Left triangularis inferior frontal gyrus
 Right posterior cingulate gyrus 6.33 0.140  < 0.001  < 0.001 Left orbital inferior frontal gyrus
5.20 0.130  < 0.001  < 0.001 Right orbital inferior frontal gyrus
4.24 0.099  < 0.001 0.007 Left triangularis inferior frontal gyrus
 Left orbito medial frontal gyrus 4.72 0.130  < 0.001 0.002 Right orbital inferior frontal gyrus
4.70 0.110  < 0.001 0.002 Right operculum inferior frontal gyrus
4.24 0.120  < 0.001 0.007 Left orbital inferior frontal gyrus
 Right orbito medial frontal gyrus 4.04 0.097  < 0.001 0.001 Left operculum inferior frontal gyrus
3.82 0.090  < 0.001 0.001 Left triangularis inferior frontal gyrus
3.40 0.081  < 0.001 0.001 Right triangularis inferior frontal gyrus
 Left anterior cingulate gyrus 4.21 0.110  < 0.001 0.001 Left triangularis inferior frontal gyrus
3.83 0.100  < 0.001 0.001 Right triangularis inferior frontal gyrus
3.82 0.093  < 0.001 0.001 Left operculum inferior frontal gyrus
 Right anterior cingulate gyrus 4.42 0.110  < 0.001 0.004 Left orbital inferior frontal gyrus
3.78 0.094  < 0.001 0.001 Left triangularis inferior frontal gyrus
3.48 0.091  < 0.001 0.001 Right triangularis inferior frontal gyrus
 Left superior frontal gyrus 4.54 0.110  < 0.001 0.003 Right operculum inferior frontal gyrus
4.37 0.110  < 0.001 0.005 Right triangularis inferior frontal gyrus
 Left precuneus 4.19 0.100  < 0.001 0.008 Left orbital inferior frontal gyrus
 Left angular gyrus 4.24 0.120  < 0.001 0.007 Left triangularis inferior frontal gyrus
 Right cuneus 4.17 0.130  < 0.001 0.008 Left calcarine sulcus
 Left calcarine sulcus 5.40 0.140  < 0.001  < 0.001 Left cerebellum 6
 Left middle cingulate gyrus 4.73 0.110  < 0.001 0.002 Left triangularis inferior frontal gyrus
SSDs < HCs
 Left putamen −5.20 −0.120  < 0.001  < 0.001 Right insular cortex
 Right putamen −5.94 −0.140  < 0.001  < 0.001 Right insular cortex
−5.20 −0.110  < 0.001  < 0.001 Left insular cortex
 Left Heschl’s gyrus −6.38 −0.160  < 0.001  < 0.001 Right Heschl’s gyrus
−4.45 −0.110  < 0.001 0.004 Right superior temporal gyrus
 Left superior temporal gyrus −4.80 −0.140  < 0.001 0.001 Right superior temporal gyrus

Whole-brain thresholded at FDR corrected p < 0.01, FDR, False Discovery Rate; HCs, Healthy Controls; SSDs, Schizophrenia spectrum disorders