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Improvement in CNS-related symptoms
| Cohort 1, n = 20 | Cohort 2, n = 32 | Cohort 3, n = 13 | |
|---|---|---|---|
| Significant improvement in CNS-related symptoms (%) | 75% (6/8) | 78.6% (11/14) | 83.3% (5/6) |
| Moderate improvement in CNS-related symptoms | 25% (2/8) | 7.1% (1/14) | 16.7% (1/6) |
| No improvement in CNS-related symptoms | 0 | 14.3% (2/14) | 0 |
| Deterioration in CNS-related symptoms | 0 | 0 | 0 |
