Table 1.
Patient demographics and clinicopathological characteristics of the training and validation cohorts
| CHSUMC cohort | P value | ATH cohort | P value | P value | |||
|---|---|---|---|---|---|---|---|
| Variables | Healthy | Patient | Healthy | Patient | |||
| (n = 120) | (n = 200) | (n = 60) | (n = 140) | ||||
| n (%) | n (%) | n (%) | n (%) | ||||
| Age (years) | 60.69 ± 8.66 | 61.06 ± 9.05 | 0.720B | 61.13 ± 9.20 | 61.24 ± 8.65 | 0.936B | 0.852B |
| Gender | |||||||
| Female | 50 (41.7) | 74 (37.0) | 0.410A | 25 (41.7) | 47 (33.6) | 0.335A | 0.566A |
| Male | 70 (58.3) | 126 (63.0) | 35 (58.3) | 93 (66.4) | |||
| Tumor depthC | |||||||
| T1/T2 | NA | 58 (29.0) | NA | 52 (37.1) | 0.126A | ||
| T3/T4 | NA | 142 (71.0) | NA | 88 (62.9) | |||
| Lymph node metastasis | |||||||
| Negative | NA | 85 (42.5) | NA | 70 (50.0) | 0.185A | ||
| Positive | NA | 115 (57.5) | NA | 70 (50.0) | |||
| Histological differentiation | |||||||
| Poor | NA | 41 (20.5) | NA | 18 (12.9) | 0.179A | ||
| Moderate | NA | 99 (49.5) | NA | 78 (55.7) | |||
| Well | NA | 60 (30.0) | NA | 44 (31.4) | |||
| Largest tumor dimension (cm) | NA | 4.86 ± 1.45 | NA | 5.01 ± 1.44 | 0.319B | ||
| TNM Stage | |||||||
| I/II | NA | 78 (39.0) | NA | 66 (47.1) | 0.148A | ||
| III/IV | NA | 122 (61.0) | NA | 74 (52.9) | |||
For categorical variables, the number of patients was shown as n (%); quantitive variables were mean ± SD
Aχ2 test was used for comparing control and patient group
BUnpaired t test was used for comparing control and patient group
CTumor depth indicated that how deeply tumor cells have invaded