Supplementary Table 3.
Effect size of HHcy and MS on cerebral stroke in different models.
| Variables | Event, n (%) | Crude Model | Model I | Model II | |||
|---|---|---|---|---|---|---|---|
| OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | ||
| Control | 175 (4.48%) | Ref | Ref | Ref | |||
| Isolated HHcy | 315 (7.47%) | 1.72 (1.43, 2.08) | <0.001 | 1.44 (1.19, 1.76) | <0.001 | 1.32 (1.07, 1.62) | 0.008 |
| Isolated MS | 192 (6.14%) | 1.40 (1.13, 1.72) | 0.002 | 1.54 (1.25, 1.91) | <0.001 | 1.78 (1.41, 2.23) | <0.001 |
| HHcy+MS | 278 (9.90%) | 2.34 (1.93, 2.85) | <0.001 | 2.26 (1.86, 2.75) | <0.001 | 2.46 (1.97, 3.08) | <0.001 |
| P for trend | <0.001 | <0.001 | <0.001 | ||||
HHcy – hyperhomocysteinemia; MS – metabolic syndrome; Ref – reference; OR – odds ratio; CI – confidence interval. Model I adjusted for age and sex. Model II adjusted for sex, BMI, smoking and drinking status, eGFR, and serum uric acid.