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. 2022 Jan 18;12(1):e706. doi: 10.1002/ctm2.706

FIGURE 3.

FIGURE 3

OIP5‐AS1 regulates inflammatory processes associated with both rheumatoid and osteoarthritis. In rheumatoid arthritis, it interacts with miR‐448 to regulate paraoxonase 1 (PON1), and is implicated in apoptosis and cell proliferation regulation. Its actions in osteoarthritis are mediated by miR‐29b‐3p to regulate apoptosis, inflammation, cell proliferation and migration