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. 2021 Dec 30;23(2):183. doi: 10.3892/etm.2021.11106

Figure 1.

Figure 1

PCA reduces the anti-proliferative effect and cell cycle arrest induced by H2O2 in NP cells. NP cells were pretreated with different concentrations of PCA (10 or 50 µg/ml) for 2 h and then stimulated with 200 µM H2O2 for 2 h in the presence or absence of PCA. (A) Cell proliferation rate at days 0, 1, 3, 5, 7 and 9 in different groups. (B) Quantification of cells in S+G2 phase of the cell cycle in different groups. (C) Cell cycle profiles of NP cells in different groups. Values are expressed as the mean ± standard deviation. *P<0.05 vs. H2O2 treatment group. NP, nucleus pulposus; PCA, p-coumaric acid.