Furusho 1991.

Methods	Study design: multicentre randomised controlled trial. Method of randomisation: unclear. Number of centres: 16. Power calculations: no. Number of patients randomised: 163 (includes 3 arms ‐ only 102 children in 2 arms relevant). Number of patients analysed: 151. Number of patients excluded from analysis: 12. Reason for exclusions from analysis: not managed according to protocol. Intention‐to‐treat analysis: no. Source of funding: not stated.
Participants	Location: Japan, 16 institutes. Inclusion criteria: children with KD enrolled within 7 days of onset October 1985 to June 1986. Exclusion criteria: recurrent KD; coronary artery lesions on admission.
Interventions	Group 1: IVIG 200 mg/kg daily for 5 days + ASA 30 to 50 mg/kg/day in 3 divided doses until fever subsided, then 10 to 30 mg/kg daily once a day until "acute reaction had disappeared". Group 2: IVIG 200 mg/kg daily for 5 days without ASA. Group 3: ASA 30 to 50 mg/kg/day in 3 divided doses until fever subsided, then 10 to 30 mg/kg daily once a day until "acute reaction had disappeared". Only children in Groups 1 and 2 considered relevant for this review.
Outcomes	Coronary artery abnormalities before day 30 of illness; and at day 30 of illness.
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	B ‐ Unclear

ASA: aspirin 
 IVIG: intravenous imunoglobulin 
 KD: Kawasaki disease