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. Author manuscript; available in PMC: 2022 Jan 18.
Published in final edited form as: Annu Rev Psychol. 2004;55:125–148. doi: 10.1146/annurev.psych.55.090902.141545

Figure 6.

Figure 6

Sleep cycle release of Hcrt. (Left) Hcrt release is maximal in active waking and REM sleep, states with high levels of activity in central motor systems, and is significantly lower in non-REM sleep. Regions that were sampled are indicated in the drawing. CI, internal capsule; HYP, lateral hypothalamus; BF, basal forebrain. (Right) Time course of Hcrt release in successive 5-minute Hcrt samples across the sleep cycle. Maximal values are seen in waking and REM sleep. (From Kiyashchenko et al. 2002)