Table 2.
Desipramine | Paroxetine | Time | Naltrexone | Placebo | Time | |
---|---|---|---|---|---|---|
Mean (SE) | Mean (SE) | F, p | Mean (SE) | Mean (SE) | F, p | |
Drinking Outcomes | ||||||
% Number of drinking days | ||||||
Pre | 55.6 (5.03) | 62.58 (4.48) | 218.49, 0.00 | 62.60 (4.70) | 58.14 (4.82) | 226.39, 0.00 |
Post | 7.62 (2.1) | 9.36 (1.92) | 9.32 (2.01) | 7.31 (2.06) | ||
% Heavy drinking days | ||||||
Pre | 50.3 (5.19) | 56.84 (4.62) | 156.8, 0.00 | 54.10 (4.85) | 54.99 (4.97) | 162.89. 0.00 |
Post | 7.09 (2.38) | 9.29 (2.12) | 8.55 (2.24) | 6.95 (2.29) | ||
Drinks per drinking days | ||||||
Pre | 17.03 (1.81) | 15.69 (1.61) | 53.57, 0.00 | 16.34 (1.66) | 16.74 (1.70) | 57.71, 0.00 |
Post | 4.19 (1.82) | 7.55 (1.62) | 6.01 (1.71) | 5.15 (1.75) | ||
Craving Outcomes | ||||||
OCDS (total scores) | ||||||
Pre | 19.00 (1.76) | 19.92 (1.57) | 8.84, 0.00 | 19.93 (1.56) | 19.94 (1.63) | 10.1, 0.00 |
Post | 8.08 (1.55) | 8.66 (1.40) | 7.18 (1.43) | 8.44 (1.37) | ||
Depression Outcomes | ||||||
HAM-D (17 items) | ||||||
Pre | 11.72 (0.74) | 11.66 (0.65) | 7.99, 0.00 | 11.89 (0.69) | 11.26 (0.69) | 8.16, 0.00 |
Post | 8.18 (0.83) | 7.61 (0.73) | 7.81 (0.75) | 7.56 (0.74) |
HAM-D, Hamilton Depression Rating Scale; OCDS, Obsessive Compulsive Drinking Scale.