TABLE 1.
All single-nucleotide polymorphisms (SNPs) and their corresponding amino acid mutations assessed by PCR/Sanger sequencing of parasite cultures for a panel of 15 P. falciparum strains
Six other SNPs can be assessed by our parasite culture PCR conditions but are not listed in this table, as all 15 strains have the wild-type allele: (pfmdr1 G293, and pfcrt T93, F145, I218, C350, G353).
Gene IDs are dhfr (PF3D7_0417200), dhps (PF3D7_0810800), pfmdr1 (PF3D7_0523000), pfcrt (PF3D7_0709000), and k13 (PF3D7_1343700).
The full names for the antimalarials are PYR (pyrimethamine), CYC (cycloguanil), SDX (sulfadoxine), MFQ (mefloquine), QN (quinine), ADQ (amodiaquine), CQ (chloroquine), PPQ (piperaquine), and ARTs (artemisinins).
3D7 is a clone of NF54; as such, these are considered to be the same strain.