FIG 2.

Replication of HIV-1 3′PPT variants. (A) C8166 cells were infected with an equal amount of the different viruses (corresponding to 1 ng CA-p24) and cultured without or with DTG. The CA-p24 level in the culture supernatant measured at 3 days (no DTG; left) or 5 days (500 nM DTG; right) after infection are shown. (B) C8166 cells were infected with a large amount of wild-type (wt) or M2 virus (corresponding to 10 ng CA-p24) and cultured with 0, 50, or 500 nM DTG. Infections were performed in triplicate, and the average CA-p24 level measured in the culture supernatant at different times after infection is shown (error bars indicate standard error).