FIG 2.

Phenotypic-genotypic correlations between tetracycline and doxycycline susceptibility testing results and tet gene content. Rows represent individual E. faecium validation set isolates. Columns represent phenotypic susceptibility testing results or tet gene content. The allelic form of tet(M) containing deletions and SNPs in the fifth TetM domain comprised the majority of isolates with phenotypic-genotypic discrepancies, and this allelic form could be distinguished from others based on tet(M) L528F. R, resistant; I, intermediate; S, susceptible; AA, amino acid.