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. 2022 Jan 18;5(6):zrab137. doi: 10.1093/bjsopen/zrab137

Table 2.

Baseline characteristics, type of surgery, and postoperative stage of patients in HRQoL analyses, sorted by three-arm randomization and pooled short-course radiotherapy comparison

Patients included in HRQoL analyses (n = 379)
Three-arm randomization
Short-course radiotherapy comparison
SRT (n = 51) SRT-delay (n = 57) LRT-delay (n = 61) SRT (n = 154) SRT-delay (n = 164)
Age (years) 64 (35–79) 63 (41–83) 65 (40–79) 65 (35–81) 64 (39–80)
Sex
 Men 33 (64.7%) 40 (70.2%) 38 (62.3%) 94 (61.0%) 97 (59.1%)
 Women 18 (35.3%) 17 (29.8%) 23 (37.7%) 60 (39.0%) 67 (40.9%)
Height from anal verge (cm)
 0–5 20 (39.2%) 25 (43.9%) 18 (29.5%) 53 (34.4%) 55 (33.5%)
 6–10 20 (39.2%) 20 (35.1%) 28 (45.9%) 60 (39.0%) 60 (36.9%)
 11–15 11 (21.6%) 12 (21.1%) 15 (24.6%) 41 (26.6%) 49 (29.9%)
Type of surgery
 AR 33 (64.7%) 34 (59.6%) 41 (67.2%) 98 (63.6%) 105 (64.0%)
 APE 17 (33.3%) 22 (38.6%) 15 (24.6%) 50 (32.5%) 56 (34.1%)
 Hartmann's 1 (2.0%) 1 (1.8%) 3 (4.9%) 6 (3.9%) 3 (1.8%)
 LE 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%)
 NR 0 (0%) 0 (0%) 2 (3.3%) 0 (0%) 0 (0%)
yPStage
 I* 28 (54.9%) 30 (52.6%) 23 (37.7%) 65 (42.2%) 74 (45.1%)
 II 14 (27.5%) 15 (26.3%) 20 (32.8%) 49 (31.8%) 38 (23.2%)
 III 9 (17.6%) 10 (17.5%) 17 (27.9%) 39 (25.3%) 44 (26.8%)
 IV 0 (0%) 0 (0%) 0 (0%) 0 (0%) 1 (0.6%)
 X 0 (0%) 2 (3.5%) 1 (1.6%) 1 (0.6%) 7 (4.3%)

Data are median (range) or n (%).

*Includes patients with complete pathological response. HRQoL, health-related quality of life; SRT, short-course radiotherapy of 5 × 5 Gy, with surgery within 1 week; SRT-delay, short-course radiotherapy of 5 × 5 Gy, with a delay of 4–8 weeks to surgery; LRT-delay, long-course radiotherapy of 25 × 2 Gy, with surgery after 4–8 weeks; AR, anterior resection; APE, abdominal perineal excision; LE, local excision; NR, no resection.