Table 6.
Variables | Subsequent non-MetSn = 218 | Subsequent new MetSn = 42 | P-value |
---|---|---|---|
Female, N (%) | 131 (60.09%) | 20 (47.62%) | 0.198 |
Current smoker, N (%) | 48 (22.02%) | 11 (26.19%) | 0.531 |
Alcohol drinker, N (%) | 88 (40.37%) | 18 (42.86%) | 0.749 |
Moderate exercise, N (%) | 107 (49.08%) | 17 (40.48%) | 0.334 |
Age (years) | 53.01 ± 6.34 | 53.49 ± 7.46 | 0.856 |
BMI (kg/m2) | 22.44 ± 2.47 | 25.07 ± 1.96 | <0.001* |
WC (cm) | 75.35 ± 7.71 | 83.19 ± 6.04 | <0.001* |
WHR | 0.85 ± 0.06 | 0.90 ± 0.05 | <0.001* |
Fat% (%) | 27.58 ± 6.76 | 30.95 ± 5.06 | 0.007* |
SFA (cm2) | 141.3 (110.3, 189.35) | 155.3 (126.6, 203.9) | 0.112 |
VFA (cm2) | 63.66 (36.42, 89.54) | 104.5 (66.68, 128.75) | <0.001* |
SBP (mmHg) | 119.27 ± 14.90 | 125.50 ± 15.26 | 0.023* |
DBP (mmHg) | 80.65 ± 16.08 | 84.01 ± 9.35 | 0.268 |
FPG (mmol/L) | 4.95 ± 0.84 | 5.09 ± 0.97 | 0.361 |
2h-PG (mmol/L) | 5.91 ± 2.79 | 6.55 ± 3.39 | 0.225 |
FINS (mIU/L) | 10.39 (6.87, 13.33) | 13.67 (8.61, 18.64) | <0.001* |
2 h insulin (mIU/L) | 37.25 (24.60, 60.30) | 56.29 (32.17, 87.59) | 0.034* |
HOMA-IR | 2.13 (1.49, 3.07) | 3.09 (1.99, 4.20) | <0.001* |
HbA1c (%) | 5.65 ± 0.63 | 5.61 ± 0.59 | 0.689 |
CHOL (mmol/L) | 5.52 ± 1.09 | 5.58 ± 0.85 | 0.738 |
TG (mmol/L) | 1.19 (0.80, 1.54) | 1.62 (1.26, 2.47) | 0.002* |
LDL-c (mmol/L) | 2.41 ± 0.56 | 2.40 ± 0.53 | 0.948 |
HDL-c (mmol/L) | 1.51 ± 0.38 | 1.28 ± 0.34 | 0.001* |
ALT (IU/L) | 19 (14, 26) | 21 (16, 27.75) | 0.657 |
AST (IU/L) | 20 (17, 23) | 20 (17.25, 24.75) | 0.688 |
CREA (mg/dl) | 0.80 ± 0.16 | 0.84 ± 0.26 | 0.709 |
BUN (mmol/L) | 16.76 ± 3.59 | 16.11 ± 3.55 | 0.318 |
UA (mg/dl) | 4.58 ± 1.39 | 5.34 ± 1.84 | 0.002* |
UACR (mg/mmol) | 4.43 (2.79, 12.09) | 4.59 (3.13, 7.03) | 0.15 |
After a 5-year follow-up, 260 non-MetS were followed up effectively, of which 42 developed new MetS. Statistical differences between subsequent new MetS and subsequent non-MetS are shown as *P < 0.05.
MetS, metabolic syndrome; BMI, body mass index; WC, waist circumference; WHR, waist-to-hip ratio; Fat%, body fat percentage; SFA, subcutaneous fat area; VFA, visceral fat area; SBP, systolic blood pressure; DBP, diastolic blood pressure; FPG, fasting blood glucose; 2h-PG, 2-h postprandial glucose; FINS, fasting serum insulin; HOMA-IR, homeostasis model assessment for insulin resistance; HbA1c, glycosylated hemoglobin A1c; TC, total cholesterol; TG, triglyceride; LDL-c, low-density lipoprotein-cholesterol; HDL-c, high-density lipoprotein-cholesterol; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CREA, serum creatinine; BUN, serum urea nitrogen; UA, uric acid; UACR, urine albumin-to-creatinine ratio.