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Time-kill activity of omadacycline against five M. abscessus isolates. M. abscessus strain ATCC 19977 (A), and clinical isolates M9510 (B), M9526 (C), M9529 (D), and M9530 (E) were exposed to omadacycline at 0.5×, 1×, 2×, 4×, 8×, and 16× MIC specific to each isolate and to no drug in cation-adjusted Mueller-Hinton broth (CAMHB). Surviving colonies were recovered on CAMHB agar in duplicate at 1, 3, and 7 days and enumerated (mean ± standard deviation [SD]).
