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Inhibition of Gag cleavage as assessed by liquid chromatography and mass spectrometry. Normalized SP1 was measured over 4 h in the presence of GSK’254 and GSK’795. (A) Wild-type VLP. (B) ΔV370-containing VLP. (C) A364V-containing VLP. SP1, spacer peptide 1; VLP, virus-like protein.
