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. 2022 Jan 14;15:311–324. doi: 10.2147/JIR.S342399

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© 2022 Jensen et al.

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Dietary fish oil enhances peritoneal concentrations of anti-inflammatory cytokines and growth factors. Mice were fed control (Ctr, grey line with grey circles) or fish oil (Fo, black line with black squares) diets for 5 weeks. They were immunized twice with mBSA with a 2-week interval and subsequently challenged intraperitoneally. Mice were sacrificed at 0, 1.5, 3, and 6 h following challenge and peritoneal fluid collected. Concentrations of IL-10 (A), IGF-1 (C), and sTNF RII (D) were determined by Luminex and TGF-β (B) by ELISA. **p < 0.01, ***p < 0.001, n = 8 for 0 and 3 h, 40 for 6 h post-challenge (A, C, and D) and 3–8 for all time-points (B). Results are shown as mean ± standard error of the mean from data collected over at least two independent experiments.