Table 3.
Association of Specific Valvular Lesion with Obstetric and Cardiovascular Outcomes
| Aortic Stenosis aOR 95% CI (n=667) | Aortic Regurgitation aOR 95% CI (n=678) | Mitral Stenosis aOR 95% CI (n=5,313) | Mitral Regurgitation aOR 95% CI (n=8,931) | Tricuspid Regurgitation aOR 95% CI (n=2,600) | Pulmonic Stenosis aOR 95% CI (n=396) | |
|---|---|---|---|---|---|---|
| OBSTETRIC COMPLICATIONS | ||||||
| Preeclampsia/Eclampsia | 2.7 (1.6–4.5) | 2.1 (1.2–3.7) | 3.0 (2.5–3.5) | 1.2 (1.0–1.4) | 2.6 (2.0–3.3) | 1.4 (0.8–3.8) |
| Gestational Hypertension | 1.1 (0.5–2.3) | 0.9 (0.4–2.0) | 1.1 (0.8–1.4) | 0.9 (0.8–1.1) | 1.2 (0.8–1.7) | - |
| Gestational Diabetes | 2.1 (1.2–3.4) | 1.4 (0.7–2.5) | 0.9 (0.7–1.1) | 1.0 (0.9–1.2) | 0.6 (0.4–0.9) | 2.5 (1.3–4.8) |
| Placenta Previa | - | 3.7 (1.2–11.5) | 0.9 (0.4–1.8) | 1.0 (0.6–1.7) | 1.6 (0.7–3.5) | - |
| Placental Abruption | 2.2 (0.7–7.0) | - | 1.4 (0.9–2.3) | 1.4 (0.9–2.1) | 1.7 (0.9–3.1) | 3.6 (1.1–11.5) |
| Hemorrhage | 1.0 (0.4–2.4) | 1.2 (0.5–2.8) | 1.6 (1.3–2.1) | 1.1 (0.8–1.4) | 1.6 (1.1–2.2) | 2.5 (1.1–5.4) |
| Premature rupture of membranes | 1.0 (0.5–1.9) | 1.2 (0.7–2.2) | 0.8 (0.6–1.0) | 1.0 (0.8–1.2) | 0.8 (0.6–1.1) | 1.3 (0.6–2.8) |
| FETAL COMPLICATIONS | ||||||
| Fetal growth restriction | 2.6 (1.4–5.0) | 4.0 (2.3–6.7) | 1.1 (0.8–1.6) | 1.1 (0.8–1.4) | 1.5 (1.0–2.2) | - |
| Stillbirth or fetal death | - | 1.6 (0.2–11.6) | 1.2 (0.5–2.4) | 0.7 (0.3–1.8) | 2.0 (0.9–4.6) | - |
| MATERNAL CARDIOVASCULAR COMPLICATIONS | ||||||
| Peripartum Cardiomyopathy | - | 65 (28–149) | 270 (227–323) | 6.4 (3.3–12.4) | 105 (76–145) | - |
| Heart failure | 23.9 (7.6–77) | 103 (54–195) | 271 (229–322) | 8.3 (4.9–13.9) | 140 (104–187) | 28.5 (6.8–119) |
| Pulmonary edema | 17.9 (4.4–72) | 37 (13–99) | 52 (39–69) | 2.4 (0.9–6.5) | 47 (31–72) | - |
| Acute Ischemic Heart Disease | 41 (5.5–300) | 42 (5.7–307) | 57 (34–96) | 10 (3.9–28) | 69 (35–136) | - |
| Arrhythmias | 6.1 (1.5–25) | 21 (9.8–45) | 30 (24–38) | 14 (11–18) | 37 (27–51) | 5.4 (0.7–39) |
*
Adjusted for age, race/ethnicity and insurance status
Per recommendations from the Healthcare Cost and Utilization Project, any cells with less than 10 events/outcomes were left blank and are marked by “ – ”