Comparison 3. Sensitivity analyses.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Random sequence generation	11	1712	Risk Ratio (IV, Random, 95% CI)	1.17 [1.09, 1.26]
1.1 Adequate (low risk)	4	830	Risk Ratio (IV, Random, 95% CI)	1.13 [1.02, 1.26]
1.2 Inadequate (high/unclear risk)	7	882	Risk Ratio (IV, Random, 95% CI)	1.23 [1.09, 1.39]
2 Allocation concealment	11	1711	Risk Ratio (IV, Random, 95% CI)	1.17 [1.09, 1.26]
2.1 Adequate (low risk)	11	1711	Risk Ratio (IV, Random, 95% CI)	1.17 [1.09, 1.26]
2.2 Inadequate (high/unclear risk)	0	0	Risk Ratio (IV, Random, 95% CI)	0.0 [0.0, 0.0]
3 Blinding	11	1712	Risk Ratio (IV, Random, 95% CI)	1.17 [1.09, 1.26]
3.1 Adequate (low risk)	1	102	Risk Ratio (IV, Random, 95% CI)	1.14 [0.97, 1.33]
3.2 Inadequate (high/unclear risk)	10	1610	Risk Ratio (IV, Random, 95% CI)	1.18 [1.08, 1.29]
4 Incomplete outcome data	11	1712	Risk Ratio (IV, Random, 95% CI)	1.17 [1.09, 1.26]
4.1 Adequate (low risk)	8	1430	Risk Ratio (IV, Random, 95% CI)	1.18 [1.07, 1.30]
4.2 Inadequate (high/unclear risk)	3	282	Risk Ratio (IV, Random, 95% CI)	1.15 [1.00, 1.33]
5 Selective reporting	11	1712	Risk Ratio (IV, Random, 95% CI)	1.17 [1.09, 1.26]
5.1 Adequate (low risk)	11	1712	Risk Ratio (IV, Random, 95% CI)	1.17 [1.09, 1.26]
5.2 Inadequate (high/unclear risk)	0	0	Risk Ratio (IV, Random, 95% CI)	0.0 [0.0, 0.0]
6 Other bias	11	1711	Risk Ratio (IV, Random, 95% CI)	1.17 [1.09, 1.26]
6.1 Adequate (low risk)	9	1371	Risk Ratio (IV, Random, 95% CI)	1.16 [1.05, 1.28]
6.2 Inadequate (high/unclear risk)	2	340	Risk Ratio (IV, Random, 95% CI)	1.21 [1.07, 1.38]
7 Hematopoietic response by definition(s)	11	1712	Risk Ratio (IV, Random, 95% CI)	1.17 [1.09, 1.26]
7.1 Hematopoietic response	8	1430	Risk Ratio (IV, Random, 95% CI)	1.18 [1.07, 1.30]
7.2 Hematologic response	2	180	Risk Ratio (IV, Random, 95% CI)	1.24 [0.80, 1.94]
7.3 Patients reaching Hb > 13 g/dL	1	102	Risk Ratio (IV, Random, 95% CI)	1.14 [0.97, 1.33]