Table 4.
Hierarchical clustering using Ward method | ||||||
Total | Cluster 1 | Cluster 2 | Cluster 3 | Kruskal–Wallis test or Chi-squared test | Mann–Whitney U test or Chi-squared test | |
Number | 136 | 25 | 83 | 28 | ||
Age (y.o.) | 42.49 | 23.8 | 46.3 | 47.89 | < 0.001*** | 1 < 3,2; p < 0.001 all*** |
Sex: Women is 1 | 0.80 | 0.80 | 0.80 | 0.84 | 0.867 | - |
Headache frequency† | 0.81 | 0.84 | 0.23 | 2.50 | < 0.001*** | 1,2 < 3; p < 0.001 all*** |
Migraine is 1 | 0.19 | 0.17 | 0.17 | 0.28 | 0.137 | - |
Duration‡ | 2.62 | 2.48 | 2.52 | 3.04 | 0.256 | - |
Use of combination-analgesic is 1 | 0.67 | 0.57 | 0.72 | 0.68 | 0.043 | p > 0.050 all |
Frequency of acute medication oral intake (days/months) | 17.08 | 15.36 | 13.53 | 29.14 | < 0.001*** | 2,1 < 3; p < 0.001 all*** |
Use of prophylactic medication is 1 | 0.07 | 0.11 | 0.06 | 0.040 | 0.272 | - |
Non-hierarchical clustering using k-means + + | ||||||
Total | Cluster 1 | Cluster 2 | Cluster 3 | Kruskal–Wallis test or Chi-squared test | Mann–Whitney U test or Chi-squared test | |
Number | 136 | 25 | 65 | 46 | ||
Age (y.o.) | 42.49 | 23.80 | 41.31 | 54.33 | < 0.001*** | 1 < 2 < 3; p < 0.001 all*** |
Sex: Women is 1 | 0.80 | 0.84 | 0.80 | 0.80 | 0.907 | - |
Headache frequency† | 0.81 | 0.84 | 0.54 | 1.17 | 0.055 | - |
Migraine is 1 | 0.19 | 0.28 | 0.17 | 0.17 | 0.457 | - |
Duration‡ | 2.62 | 2.48 | 2.62 | 2.70 | 0.827 | - |
Use of combination-analgesic is 1 | 0.67 | 0.68 | 0.72 | 0.57 | 0.218 | - |
Frequency of acute medication oral intake (days/months) | 17.08 | 15.36 | 15.74 | 19.91 | < 0.001*** |
1,2 < 3; p = 0.021 for 1 vs 3* p = 0.005 for 2 vs 3** |
Use of prophylactic medication is 1 | 0.07 | 0.04 | 0.06 | 0.11 | 0.500 | - |
*; p < 0.050, **; p < 0.010 ***; p < 0.001, †; Ordinal scale for headache frequency as follows. 0; 15–19 days/months, 1; 20–24 days/months, 2; 25–29 days/months, 3; everyday, ‡; Ordinal scale for headache duration as follows. 0; less than 60 min, 1; 1–3 h; 2; 4–8 h, 3; 9–24 h, 4; 2–3 days, 5; 4–7 days, 6; over 8 days