Skip to main content
. 2022 Jan 19;43(6):3811–3822. doi: 10.1007/s10072-021-05831-w

Table 4.

Means of each variable among clusters

Hierarchical clustering using Ward method
Total Cluster 1 Cluster 2 Cluster 3 Kruskal–Wallis test or Chi-squared test Mann–Whitney U test or Chi-squared test
Number 136 25 83 28
Age (y.o.) 42.49 23.8 46.3 47.89  < 0.001*** 1 < 3,2; p < 0.001 all***
Sex: Women is 1 0.80 0.80 0.80 0.84 0.867 -
Headache frequency† 0.81 0.84 0.23 2.50  < 0.001*** 1,2 < 3; p < 0.001 all***
Migraine is 1 0.19 0.17 0.17 0.28 0.137 -
Duration‡ 2.62 2.48 2.52 3.04 0.256 -
Use of combination-analgesic is 1 0.67 0.57 0.72 0.68 0.043 p > 0.050 all
Frequency of acute medication oral intake (days/months) 17.08 15.36 13.53 29.14  < 0.001*** 2,1 < 3; p < 0.001 all***
Use of prophylactic medication is 1 0.07 0.11 0.06 0.040 0.272 -
Non-hierarchical clustering using k-means +  + 
Total Cluster 1 Cluster 2 Cluster 3 Kruskal–Wallis test or Chi-squared test Mann–Whitney U test or Chi-squared test
Number 136 25 65 46
Age (y.o.) 42.49 23.80 41.31 54.33  < 0.001*** 1 < 2 < 3; p < 0.001 all***
Sex: Women is 1 0.80 0.84 0.80 0.80 0.907 -
Headache frequency† 0.81 0.84 0.54 1.17 0.055 -
Migraine is 1 0.19 0.28 0.17 0.17 0.457 -
Duration‡ 2.62 2.48 2.62 2.70 0.827 -
Use of combination-analgesic is 1 0.67 0.68 0.72 0.57 0.218 -
Frequency of acute medication oral intake (days/months) 17.08 15.36 15.74 19.91  < 0.001***

1,2 < 3;

p = 0.021 for 1 vs 3*

p = 0.005 for 2 vs 3**

Use of prophylactic medication is 1 0.07 0.04 0.06 0.11 0.500 -

*; p < 0.050, **; p < 0.010 ***; p < 0.001, †; Ordinal scale for headache frequency as follows. 0; 15–19 days/months, 1; 20–24 days/months, 2; 25–29 days/months, 3; everyday, ‡; Ordinal scale for headache duration as follows. 0; less than 60 min, 1; 1–3 h; 2; 4–8 h, 3; 9–24 h, 4; 2–3 days, 5; 4–7 days, 6; over 8 days