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miR-21 inhibited the activation of the apoptosis pathway elevated by GAS5. (a) Representative images of Western blot assays detecting Bax, caspase 3, and beta-actin in extracts from the MCF-7 cells irradiated at a dose of 8 Gy. (b, c) Quantitative analysis of the raw density of Bax and caspase 3 compared to that of beta-actin with ImageJ software. ∗P < 0.05 and ∗∗P < 0.01 vs. the GAS5-overexpressing group.
