Table 2:
Comparisons between patients with PNMD and patients without PNMD
| Variables | Univariate analysis |
Multivariate analysis |
||||
|---|---|---|---|---|---|---|
| Absence of PNMD (n = 403) | Presence of PNMD (n = 24) | P-value | OR | 95% CI | P-value | |
| Age (years), mean ± SD | 60.4 ± 15.9 | 51.2 ± 16.1 | 0.009 | 0.996 | 0.927–1.070 | 0.915 |
| Gender, n/% | 0.265 | |||||
| Female | 134/33.3 | 5/20.8 | ||||
| Male | 269/66.7 | 19/79.2 | ||||
| Comorbidity rate, n/% | 313/77.7 | 18/75.0 | 0.761 | |||
| Pre-existing lung disease, n/% | 56/13.9 | 4/16.7 | 0.761 | |||
| Side of pneumonia, | 1.000 | |||||
| Unilateral | 43/10.7 | 2/8.3 | ||||
| Bilateral | 360/89.3 | 22/91.7 | ||||
| TSS, mean ± SD | 7.2 ± 4.0 | 8.9 ± 5.4 | 0.198 | |||
| Mode of breathing, n/% | 0.400 | |||||
| NIV | 71/17.6 | 2/8.3 | ||||
| MV | 332/82.4 | 22/91.7 | ||||
| PEEP (cmH2O),a mean ± SD | 8.8 ± 1.4 | 9.8 ± 1.0 | <0.001 | 1.082 | 0.725–1.616 | 0.698 |
| PIP (cmH2O),a mean ± SD | 25.9 ± 4.4 | 32.3 ± 6.6 | <0.001 | 1.238 | 1.091–1.378 | <0.001 |
| TV (ml/kg),a mean ± SD | 457.4 ± 83.0 | 445.6 ± 102.3 | 0.580 | |||
| PaO2/FiO2 ratio (mmHg),a mean ± SD | 176.6 ± 67.6 | 111.7 ± 51.5 | <0.001 | 0.982 | 0.971–0.994 | 0.004 |
| Compliance (ml/cmH2O),a mean ± SD | 33.3 ± 10.2 | 26.5 ± 7.1 | <0.001 | 0.990 | 0.923–1.063 | 0.775 |
a
Calculation was made in mechanically ventilated patients (n = 354).
CI: confidence interval; MV: invasive mechanical ventilation; NIV: non-invasive mechanical ventilation; OR: odds ratio; PEEP: positive end-expiratory pressure; PIP: peak inspiratory pressure; PNMD: pneumomediastinum; SD: standard deviation; TSS: overall lung total severity score; TV: tidal volume. Boldface indicates statistical significance.