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. 2019 Sep 25;5(4):107–109. doi: 10.20407/fmj.2019-007

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This is an Open access article distributed under the Terms of Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

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Microscopic and immunohistochemical features of adenosquamous carcinoma of the cecum. (a) Histological findings. Blue: adenocarcinoma (AD) component; red: squamous cell carcinoma (SCC) component (hematoxylin and eosin [H&E]; loupe). (b) Ductal and cribriform pattern of atypical columnar AD cells (H&E; 200× magnification). (c) Island pattern by dysplastic squamous epithelium with keratinization in SCC component (H&E; 200× magnification). Immunohistochemistry shows SCC component is (d) strongly 34βE12+, (e) p40+, and (f) focally positive for carcinoembryonic antigen ( 200× magnification for each).