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. 2022 Jan 14;17:165–180. doi: 10.2147/COPD.S345263

Table 3.

When to Prefer Triple Therapy FDCs Over Dual Bronchodilation

Immediate choice in
• Patients who present for the first time, and have severe airway obstruction (FEV1 <50%) and are symptomatic
• Patients who have had frequent (≥2) moderate or severe exacerbations (≥1 hospitalisation) in the previous year
• Patients who have peripheral eosinophilia (>300 cells·μL−1)
• Patients with significant lung function decline
• Patients discharged from hospital after a COPD exacerbation.