Table 3.
Mean differences and 95% confidence intervals for quality of life scores by comorbidity status*
| Blood vessel diseases | Mental health | Diabetes | Obesity | ||
|---|---|---|---|---|---|
| Mean difference (95% Confidence Interval) | |||||
| SF-12† Physical | Crude | -4.18 (-6.61, -1.75) | -1.55 (-4.06, 0.96) | -4.20 (-7.93, -0.47) | -5.17 (-8.19, -2.16) |
| Adjusted§ | -2.18 (-4.68, 0.31) | -1.68 (-4.11, 0.74) | -0.94 (-4.67, 2.78) | -4.32 (-7.30, -1.34) | |
| SF-12† Mental | Crude | 2.93 (-0.31, 6.17) | -8.42 (-11.48, -5.37) | 4.54 (-0.34, 9.43) | -2.15 (-6.20, 1.89) |
| Adjusted§ | 2.74 (-0.66, 6.14) | -7.84 (-10.93, -4.74) | 1.40 (-2.07, 4.88) | -1.65 (-5.70, 2.40) | |
| EPIC‡ Urinary | Crude | -3.21 (-8.39, 1.96) | -4.44 (-9.62, 0.74) | -9.98 (-17.71, -2.26) | -4.30 (-10.73, 2.12) |
| Adjusted | -1.70 (-7.43, 4.03) | -4.60 (-10.12, 0.91) | -7.80 (-16.20, 0.60) | -4.04 (-10.83, 2.74) | |
| EPIC‡ Sexual | Crude | -3.64 (-9.83, 2.55) | -3.15 (-9.36, 3.07) | -2.86 (-12.3, 6.54) | -5.87 (-13.55, 1.82) |
| Adjusted§ | 0.79 (-5.73, 7.32) | -3.96 (-10.26, 2.33) | 1.20 (-8.45, 10.86) | -4.63 (-12.35, 3.09) | |
| EPIC‡ Bowel | Crude | -3.41 (-7.13, 0.30) | -3.54 (-7.27, 0.18) | -3.39 (-9.03, 2.26) | -3.38 (-8.01, 1.25) |
| Adjusted§ | -2.89 (-6.75, 0.98) | -2.92 (-6.66, 0.81) | -2.18 (-7.93, 3.57) | -2.84 (-7.44, 1.77) | |
| EPIC‡ Hormonal | Crude | -1.26 (-6.27, 3.75) | -11.98 (-16.72, -7.26) | 1.45 (-6.13, 9.04) | -8.22 (-14.34, -2.10) |
| Adjusted§ | 2.07 (-2.99, 7.13) | -12.29 (-16.83, -7.74) | 4.59 (-2.87, 12.06) | -7.13 (-13.13, -1.13) | |
⁎
Bold values are statistically significant at P < .05. Participants were compared using t-tests.
†
The 12-item Short-Form Health Survey (SF-12) is normed with a mean of 50, with higher scores indicating better quality of life
‡
The Expanded Prostate Cancer Index Composite (EPIC) is scored from 0 to 100, with higher scores indicating better quality of life.
§
Analyses of blood vessel disease, mental health, and diabetes are adjusted for age, race, years since prostate cancer diagnosis, prostate cancer treatment, and obesity. Analyses of obesity are adjusted for age, race, years since prostate cancer diagnosis, and prostate cancer treatment.