Table 5.
Hybridization-based methods registered in the Genetic Testing Registry (GTR) for biomarker analysis
| Hybridization-based methods ‘Molecular Genetics’ | Percentage of drugs (‘Testing recommended’ and ‘Testing required’) (%) | Percentage of drugs (‘Actionable PGx’) (%) |
|---|---|---|
| Reverse dot blot hybridization | 1.7 | – |
| PCR with allele specific hybridization | 41.4 | 37.5 |
| Microarray | 36.21 | 68.8 |
| CGH | 8.6 | 21.9 |
| FISH | 20.7 | 3.1 |
Most frequenty applied techniques for both listings (‘Testing recommended’/‘Testing required’ and ‘Actionable PGx’) are shaeded in bold
FISH fluorescence in situ hybridization, CGH comparative genomic hybridization