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. 2021 Dec 14;26(1):89–103. doi: 10.1007/s40291-021-00567-x

Table 5.

Hybridization-based methods registered in the Genetic Testing Registry (GTR) for biomarker analysis

Hybridization-based methods ‘Molecular Genetics’ Percentage of drugs (‘Testing recommended’ and ‘Testing required’) (%) Percentage of drugs (‘Actionable PGx’) (%)
Reverse dot blot hybridization 1.7
PCR with allele specific hybridization 41.4 37.5
Microarray 36.21 68.8
CGH 8.6 21.9
FISH 20.7 3.1

Most frequenty applied techniques for both listings (‘Testing recommended’/‘Testing required’ and ‘Actionable PGx’) are shaeded in bold

FISH fluorescence in situ hybridization, CGH comparative genomic hybridization