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. 2022 Jan 7;26(1):117–127. doi: 10.1007/s40291-021-00573-z

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 3 — The mRNA expression level of glucocorticoid receptor (GR) and cell viability. a The mRNA expression level of the target gene (GR) in cells treated with each antisense oligonucleotide (ASO) at a concentration in the range of 3.13–50 nM by qRT-PCR. b The cell viability evaluation in cells treated with each ASO at a concentration in the range of 3.13–50 nM by WST-assay. c The mRNA expression level of GR in cells treated with each ASO at concentrations of 40 nM and 45 nM for gap-GR14, 60 nM for gap-GR18-1, 40 nM and 45 nM for gap-GR18-2, and 12.5 nM for gap-GR18-3 by qRT-PCR. The bar graph shows the mean ± standard deviation (n = 4)