Table 1.
Healthy | Nephrotic | |||
---|---|---|---|---|
Habp2+/+ | Habp2−/− | Habp2+/+ | Habp2−/− | |
Total Na+ intake, µmol 24 h−1 | 245 ± 26 | 265 ± 38 | 291 ± 38 | 261 ± 39 |
Urinary Na+ excretion, µmol 24 h−1 | 103 ± 22 | 108 ± 13 | 12 ± 4# | 10 ± 3# |
Fecal Na+ excretion, µmol 24 h−1 | 24 ± 4 | 37 ± 4* | 13 ± 3# | 11 ± 1# |
Na+ balance, µmol 24 h−1 | 118 ± 22 | 120 ± 33 | 266 ± 36# | 239 ± 37# |
Arithmetic means ± SEM (n = 6 each). Note that the body weight was similar in Habp2+/+ and Habp2−/− mice (25.6 ± 0.9 g vs. 24.7 ± 1.3 g, p = 0.59). #Significant difference between healthy and nephrotic mice; *significant difference between genotypes