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. 2022 Jan 18;12:888. doi: 10.1038/s41598-021-04755-x

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Working hypothesis of lipid related genes and proteins in primary bovine hepatocytes during the liver lipid accumulation phase (left panel) and the liver lipid recovery phase (right panel). The gray box insert within each panel represents the associations between PNPLA3, transcription factors, and genes where potential for regulatory influence exists. Relative abundance between panels are shown visually with line weight and quantity. Arrows between genes and proteins indicate associative relationships based on published research across species and the current data and do not denote directionality of regulation. Created with BioRendeder.com.