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. 2022 Jan 18;13:373. doi: 10.1038/s41467-022-27989-3

Fig. 1. Background and concept design.

Fig. 1

a Representative examples of axially chiral axially chiral N-heterobiaryls. b State of the art of CADA using pyridine as an electrophile. c State of the art of CADA using pyridine as a nucleophile. d AASI for the synthesis of axially chiral enamides. e Atroposelective cycloisomerization to axially chiral arylquinolizones.