Table 2.
Population (Signif. Stages Strat.When not both) | Disease vs Control | Variation across the cycle | ||||||
---|---|---|---|---|---|---|---|---|
Enriched in | Signif. | Control | Endo | |||||
Phase | ||||||||
Strat. | PE | ESE | MSE | PE | ESE | MSE | ||
γδTcells | Control (n = 34) | PE | +++ ◊ | ++~ | + ◊~ | ++ | ++ | ++ |
CD4+ memory T cells | PE | +++ | +++ | +++ | + ◊ | +++ | ++ ◊ | |
Th2 cells | PE, ESE | +++ ◊ | +++~ | + ◊ ~ | ++ ◊ | ++ | + ◊ | |
DC | Endo (n = 71) | All | + | + | ++ | +++ ◊ | ++ ◊ | +++ |
iDC (stages III-IV) | PE | +++ *◊ | ++ * | ++ ◊ | +++ *◊ | ++ * | ++ ◊ | |
aDC | All | + | + | ++ | +++ | ++ | +++ | |
pDC | PE, MSE | + ◊ | + | ++ ◊ | ++ ◊ | ++ ~ | +++ ◊~ | |
Monocytes | PE, MSE | + | + | + | ++ ◊ | + ~ | ++ ◊~ | |
Macrophages | PE, MSE | + ◊ | + ~ | ++ ◊~ | ++ ◊ | ++ ~ | +++ ◊~ | |
Macrophages M1 | All | + | + ~ | ++ ~ | +++ | ++ ~ | +++ ~ | |
Macrophages M2 | All | + ◊ | + ~ | ++ ◊~ | +++ * | ++ *~ | +++ *~ | |
NK cells (Stages III-IV) | None | + ◊ | + | ++ ◊ | + ◊ | ++ ~ | +++ ◊~ | |
Neutrophils | PE | + | + | + | + | + | + | |
Eosinophils | All | + ◊ | + | ++ ◊ | ++ * | + * | ++ | |
Basophils | PE, MSE | + ◊ | ++ | +++ ◊ | +++ | ++ ~ | +++ ~ | |
CD8+ Tem | All | + ◊ | + ~ | ++ ◊~ | ++ ◊ | ++ ~ | +++ ◊~ | |
CD4+ naïve | PE, ESE | + ◊ | + ~ | +++ ◊~ | ++ ◊ | ++ ~ | +++ ◊~ | |
CD4+ Tcm | PE, ESE | + ◊ | + ~ | +++ ◊~ | ++ | ++ ~ | +++ ~ | |
CD4+ Tem | All | + ◊ | + ~ | ++ ◊~ | +++ * | ++ *~ | +++ ~ | |
Th1 (stages I-II) | PE, MSE | +++ ◊ | ++ | + ◊ | +++ *◊ | ++ * | ++ ◊ | |
Endothelial cells | PE | ++ | ++ | ++ | +++ | ++ | +++ | |
mv Endothelial | All | + | + ~ | ++ ~ | +++ * | ++* ~ | +++ ~ | |
ly Endothelial | All | ++ * | + * | + | +++ * | ++ * | +++ | |
Epithelial cells | PE, MSE | + ◊ | ++ | +++ ◊ | + ◊ | ++ ~ | +++ ◊~ | |
Keratinocytes | All | + ◊ | ++ | +++ ◊ | +++ | ++ | +++ | |
Skeletal muscle cells | PE, MSE | + | + | + | ++ | ++ | ++ | |
Neurons (phase strats only) | PE, MSE | +++ ◊* | ++ * | + ◊ | ++ *◊ | + * | + ◊ | |
Astrocytes (phase strats only) | MSE | +++ ◊ | ++ | + ◊ | +++ *◊ | ++ * | ++ ◊ | |
Erythrocytes (phase strats) | MSE | +++ ◊ | ++ ~ | + ◊~ | ++ ◊ | ++ | + ◊ | |
MPP | All | + ◊ | + ~ | ++ ◊~ | ++ | + ~ | ++ ~ | |
HSC | PE, ESE | + *◊ | ++ * | +++ ◊ | +++ | +++ | +++ |
Significant differences between: * = PE and ESE; ~ = ESE and MSE; ◊ = PE and MSE.
Abundance of the cell type = +/++/+++.
Unstrat., Unstratified.