Table 1.

Principal eligibility criteria for patients utilized for patient profile generation

Inclusion Criteria

Exclusion Criteria

Males and females fulfilling 1997 American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus Age ≤ 18 years at the time of index kidney biopsy‡ Time of index kidney biopsy between January 2008 and June 2018 Index kidney biopsy consistent with new diagnosis of LN¥ Class III, III/V, Class IV, or IV/V as per the ISN/RPS† Classification Criteria of LN Induction therapy with cyclophosphamide or mycophenolate mofetil

Use of rituximab within six months of diagnosis with proliferative LN Chronic medical conditions, other than SLE, that necessitate chronic CS use Renal replacement therapy requirement within 6 months of index kidney biopsy History of kidney transplant Follow up for LN at the center for fewer than 6 months after index kidney biopsy Lack of biopsy report for index kidney biopsy in patient’s medical record

^‡Patient could have had other renal biopsies indicating presence of other classes of LN

^¥Lupus nephritis

^†International Society for Nephrology/ Renal Pathology Society