Table 4.

Uni- and multivariable analysis of demographic, clinical, laboratory and radiologic parameters in pediatric TBM with and without hypoglycorrhachia.

Univariable analysis
	p-value	OR (95% CI)
Definite TBM	0.78	1.08 (0.62–1.87)
Male	0.57	0.88 (0.57–1.36)
Median age	0.35
Vomiting	0.14	1.42 (0.89–2.27)
Fever	0.62	1.13 (0.70–1.81)
Convulsions	0.82	0.95 (0.60–1.50)
Symptom duration >5 days	0.02	1.87 (1.09–3.20)
Median symptom duration	0.53
Weight faltering/loss	0.14	1.41 (0.90–2.22)
GCS <15	0.48	1.20 (0.72–2.00)
TBM Stage I	0.09	0.37 (0.12–1.16)
Stage IIa	0.99	1.00 (0.58–1.73)
Stage IIb	0.33	1.28 (0.78–2.08)
Stage III	0.76	0.94 (0.61–1.44)
Stroke (hemiparesis and/or radiologic infarction)	0.13	1.43 (0.90–2.27)
Cranial nerve palsy	0.39	1.25 (0.75–2.07)
Raised ICP	0.39	0.79 (0.47–1.34)
Brainstem dysfunction	0.46	1.20 (0.74–1.93)
Median serum sodium	0.32
CSF leucocytes 10–500 cells/L	<0.01	3.00 (1.47–6.12)
CSF lymphocyte predominance	0.87	1.05 (0.59–1.88)
CSF protein >1 g/L	<0.01	2.51 (1.49–4.20)
Basal meningeal enhancement	0.31	1.34 (0.76–2.36)
Tuberculoma (s)	0.54	0.82 (0.43–1.55)
Hydrocephalus	0.20	1.63 (0.77–3.46)
Non-communicating hydrocephalus	0.05	1.64 (0.99–2.71)
Death	0.84	1.09 (0.47–5.54)
Multivariable analysis
	p -value	aOR (95% CI)
Symptom duration >5 days	0.12	1.61 (0.89–2.93)
CSF leucocytes 10–500 cells/L	0.06	2.21 (0.98–5.01)
CSF protein >1 g/L	<0.01	2.52 (1.44–4.40)
Non-communicating hydrocephalus	0.10	1.58 (0.92–2.71)

TBM, tuberculous meningitis; OR, odds ratio; CI, confidence interval; ICP, intracranial pressure; CSF, cerebrospinal fluid; aOR, adjusted odds ratio. The bold values reflect significant p value of ≤.