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. 2022 Jan 5;15:674439. doi: 10.3389/fninf.2021.674439

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Copyright © 2022 Li, Wang, Werner, Xie, Guan and Hilgetag.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ΔC and ΔSTD values for the original (RAW) and corresponding values after vignetting correction. (A,B) Represent the effect if performing brightness and contrast correction. In (C,D) (right sides), only brightness was corrected. Similarly, (E,F) show the data for contrast-only correction. The shown data are averaged over the obtained normalized data for the three studied measures (neural activity, absolute differences of neural activity, relative differences) and the different layer compartments. ^Δp > 0.05, *p < 0.05; **p < 0.01, ***p < 0.001, t-test.