Table 4.

Regression coefficients (β-values) with 95% confidence intervals from linear regression analyses which were utilized to investigate the associations between pre-existing comorbidities and the progression of desaturation parameters between the two PSG recordings. β-values correspond to the expedited increase in parameter value between the PSG recordings that is associated with the existence of the comorbidity at baseline.

	ΔODI	ΔDesSev	ΔDesDur	Δavg. DesArea	Δavg. DesDur
Any-Comorbidity	0.98 (−0.02, 1.99)	0.03 (−0.01, 0.06)	0.74 (−0.05, 1.52)	−0.98 (−3.17, 1.21)	−0.22 (−0.77, 0.32)
Hypertension	0.98 (−0.05, 2.01)	0.03 (−0.01, 0.06)	0.74 (−0.06, 1.54)	−1.05 (−3.31, 1.20)	−0.21 (−0.78, 0.35)
Diabetes	3.59 (1.78, 5.39)**	0.08 (0.02, 0.14)*	2.60 (1.22, 3.98)**	−3.59 (−8.00, 0.81)	−1.41 (−2.54, −0.27)*
CVD	2.73 (1.15, 4.32)**	0.06 (0.00, 0.11)	1.85 (0.62, 3.08)**	−1.19 (−4.97, 2.59)	−0.38 (−1.34, 0.58)

Regression analyses were adjusted for sex, age, baseline values of body mass index, neck circumference-height ratio, ODI, avg. DesArea, and avg. DesDur, and changes in body mass index and neck circumference-height ratio between the PSG recordings. Statistically significant association between pre-existing comorbidity and the expedited progression of the parameter (Δ) is marked with an asterisk (p<0.05, *; Bonferroni-corrected threshold p<0.01, **). Participants free from hypertension, diabetes, and CVD (i.e. No-Comorbidity group) were used as a reference group in the case of all comorbidities. ODI = oxygen desaturation index, DesSev = desaturation severity, DesDur = desaturation duration, avg. DesArea = average desaturation area of individual desaturation events, avg. DesDur = average desaturation duration of individual desaturation events, CVD = cardiovascular disease (consists of myocardial infarction, heart failure, coronary angioplasty, coronary artery bypass graft, and stroke).