Table 5.
Desaturation parameter values at the baseline, after the follow-up, and changes in parameter values between the two PSG recordings for participants with and without incident CVD after the baseline measurement.
NoIncident-CVD | Incident-CVD | Incident-CVDbetween | Incident-CVDafter | |
---|---|---|---|---|
n (male%) | 1149 (40.9) | 115 (62.6) | 37 (67.6) | 78 (60.3) |
Time between PSGs (y) | 5.3 (0.3) | 5.2 (0.4)## | 5.3 (0.4) | 5.2 (0.3)##* |
Total follow-up time (y) | 12.1 (1.5) | 11.8 (1.6) | 12.1 (1.1) | 11.6 (1.8) |
ODI (1/h) | ||||
Baseline (1st PSG) | 3.0 (1.4, 8.0) | 4.6 (2.1, 9.0)# | 3.8 (1.8, 7.2) | 4.6 (2.1, 9.6)# |
Follow-up (2nd PSG) | 7.9 (3.9, 15.6) | 10.0 (5.8, 18.3)# | 9.5 (6.4, 19.0) | 10.2 (5.5, 17.9)# |
Change | 4.0 (1.2, 8.6) | 5.1 (2.2, 11.2)# | 4.9 (2.4, 12.2) | 5.1 (1.8, 11.0) |
DesSev (%) | ||||
Baseline (1st PSG) | 0.08 (0.03, 0.21) | 0.11 (0.04, 0.24)## | 0.10 (0.03, 0.20) | 0.12 (0.05, 0.26)## |
Follow-up (2nd PSG) | 0.19 (0.09, 0.40) | 0.24 (0.13, 0.49)## | 0.21 (0.14, 0.46) | 0.26 (0.13, 0.53)# |
Change | 0.08 (0.02, 0.21) | 0.12 (0.05, 0.29)# | 0.13 (0.06, 0.25) | 0.12 (0.03, 0.30) |
DesDur (%) | ||||
Baseline (1st PSG) | 2.6 (1.0, 6.8) | 3.9 (1.7, 7.8)## | 3.5 (1.2, 6.1) | 4.1 (1.9, 8.2)## |
Follow-up (2nd PSG) | 6.8 (3.3, 13.4) | 8.6 (4.8, 16.0)## | 8.4 (5.0, 14.8) | 9.0 (4.7, 17.2)# |
Change | 3.4 (1.0, 7.1) | 4.7 (2.2, 9.1)## | 5.2 (2.7, 8.7)# | 4.7 (1.8, 9.3) |
avg. DesArea (s%) | ||||
Baseline (1st PSG) | 87.8 (70.2, 108.9) | 95.7 (78.2, 113.0)# | 94.4 (70.4, 111.6) | 97.4 (81.1, 113.5)# |
Follow-up (2nd PSG) | 84.9 (70.0, 103.3) | 90.1 (77.0, 109.0)# | 91.4 (73.0, 105.9) | 89.7 (77.3, 112.5)# |
Change | −1.8 (−19.2, 15.6) | −5.5 (−17.9, 14.9) | −5.5 (−16.7, 22.2) | −6.2 (−18.5, 12.9) |
avg. DesDur (s) | ||||
Baseline (1st PSG) | 28.3 (23.1, 33.9) | 30.6 (26.0, 36.1)## | 29.0 (24.2, 34.1) | 31.1 (26.5, 36.9)## |
Follow-up (2nd PSG) | 28.9 (24.6, 33.5) | 30.8 (27.0, 34.9)## | 31.0 (26.9, 34.2) | 30.6 (27.0, 35.9)## |
Change | 0.6 (−4.6, 5.9) | −0.6 (−4.8, 5.4) | 1.0 (−3.6, 6.5) | −1.3 (−4.9, 5.3) |
Parameter values are presented as medians and interquartile ranges. Incident-CVD group consist of participants who developed CVD after the baseline PSG examination. This group is further divided into Incident-CVDbetween and Incident-CVDafter groups based on whether the first CVD occurred before or after the follow-up PSG, respectively. Mann-Whitney U test was used to investigate statistical significance of differences between incident CVD groups and NoIncident-CVD group (p<0.05, #; p<0.01, ##), and between Incident-CVDbetween and Incident-CVDafter groups (p<0.05, *; p<0.01, **). ODI = oxygen desaturation index, DesSev = desaturation severity, DesDur = desaturation duration, avg. DesArea = average desaturation area of individual desaturation events, avg. DesDur = average desaturation duration of individual desaturation events. CVD = cardiovascular disease (consists of myocardial infarction, heart failure, coronary angioplasty, coronary artery bypass graft, and stroke.