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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: Breast Cancer Res Treat. 2021 Nov 24;191(2):459–469. doi: 10.1007/s10549-021-06455-6

Table 4.

Factors Associated with Longitudinal Scores for Well-Being Outcomes1

Physical Well-being Functional Well-being Emotional Well-being
Covariates β (95% CI) β (95% CI) β (95% CI)
Age, per 1 year increase .01 (−.10 – .11) .05 (−.09 – .19) .02 (−.08 – .11)
CogAge vs TLC 3.04 (1.66 – 4.43)*** .06 (−1.69 – 1.82) 6.49 (5.25 – 7.74)***
High school vs. <=HS education 10.2 (−.27 – 2.30) 1.63 (.00 – 3.26)* .87 (−.28 – 2.02)
IADL, per increase in limitation −.74 (−1.23 - −.24)** .89 (−1.52 – .25)** −.33 (−.78 – .12)
Hormone Therapy (Yes versus No) 1.02 (.00 – 2.05) 1.55 (.25 – 2.84)* .61 (−.31 – 1.53)
Impact of Taxanes
Taxane vs. non taxane regimen .89 (−.66 – 2.23) −.03 (−1.72 – 1.71) −.50 (−1.64 – .64)
Time effect, pre-treatment to 12-month .35 (−.53 – 1.24) 1.02 (.08 – 1.97)* 1.38 (.83 – 1.93)***
Taxane group × pre-treatment to 12-month −.62 (−2.36 – 1.12) −.20 (−2.08 – 1.68) −.60 (−1.70 – .50)
Time effect, 12- to 36-months .47 (−.16 – 1.10) .39 (−.28 – 1.08) .06 (−.34 – .45)
Taxane group × 12- to 36 months −.15 (−1.36 – 1.07) −.17 (−1.47 – 1.14) −.02 (−.78 – .74)
*

p < .05,

**

p < .01,

***

p < .001

1

Results for piecewise multilevel models modeling change in well-being outcomes. Sample reference group is TLC; Education reference group is high school completion; treatment group reference is chemotherapy with taxane.