Diffusion-MRI tractography showing fiber bundles connected to different subregions of the left PFC and four MDD-related deep-brain regions: (a)-(c) illustrate the fiber bundles that connect the amPFC (yellow), lPFC (magenta) and the dACC, the rACC, and the genu of CC, respectively, and (d) illustrate the fiber bundles between the amPFC and the SGC. There is no connection between lPFC and SGC.